HAPPY MOTHER’S DAY!
Leslie Haywood “Grill Charms” Founder Joins “La Bubé Athletica” As Brand Model
LESLIE HAYWOOD JOINS THE BREAST CHEK KIT, INC. AS BRAND MODEL FOR LAUNCH OF LA
BUBÉ ATHLETICA ACTIVE WEAR TARGETING POST MASTECTOMY WOMEN
Atlanta, GA – The Breast Chek Kit, Inc., inventors of the patented Breast Chek Kit Shirt for teaching breast self-examination, recently announced the launch of an innovative, new active wear line targeting women who have had mastectomies.
The La Bubé Athletica line incorporates special technical features and fabrics specifically to address the post-surgical needs of women as they move toward exercise and the rehabilitation process. The stylish workout and lifestyle wear is for all women and shows support for those who are battling breast cancer as well as those who have survived.
While other mastectomy manufacturers have produced functional intimate wear such as bras, camisoles and swimsuits, with built-in pockets, La Bubé Athletica is the first to offer active wear with hidden pockets for prosthetics or breast enhancers.
The line includes functional classic tanks, racer back tops, camisoles, and jackets, with matching hoodies, pants, vests and accessories to complement the collection.
According to Linda Lewis, President and Chief Executive Officer of The Breast Chek Kit, Inc., “the workout wear will fill a void in the market. La Bubé Athletica is a unique lifestyle line that will appeal to women who were active and stylish before their surgery and who fully intend to remain active afterwards. The line is so stylish that every woman, who enjoys wearing beautiful active wear as they run errands, travel, and shop, will want to wear La Bubé Athletica for its amazing function, style and unparalleled comfort. When choosing an ambassador and model for the collection, we wanted a person that represented the true embodiment of the brand, a woman with fierce tenacity, strength, an audacity to endure the journey but yet remain humble. Leslie Wombwell Haywood, a friend and fellow breast cancer survivor who had endured a bilateral mastectomy and 2 reconstructive procedures in 2006 fit perfectly. As a wife, mother, and the inventor of Grill Charms, Keychains for a Cure, a competitor on ABC’s Shark Tank, exercise enthusiast and so much more, Leslie was simply a natural. Her zeal for living life in the moment with her contagious laugh and constant smile shows her strength of purpose to Trust The Journey in all she does”.
A portion of all proceeds of The Beast Chek Kit, La Bubé Athletica, Grill Charms Pink Collection, and Keychains for a Cure go toward breast cancer education and research.
For more information about La Bubé Athletica, go to: www.wearlabube.com. Media inquiries may contact Stanley Yorker, syorker@wearlabube.com. Retailers and Buyer inquiries or to schedule an appointment may be addressed to: sales@wearlabube.com.
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New Breast Cancer Screening Numbers for Minorities Encouraging, But More Work Needed to Reduce Disparities Says Susan G. Komen for the Cure®
New CDC Numbers Underscore Urgent Need to Reach Minorities and Uninsured Women
WASHINGTON, D.C. – Jan. 27, 2012 – Officials with Susan G. Komen for the Cure hailed new government figures that found the gap between white and minority women is narrowing when it comes to breast cancer screening rates, but expressed concern that the numbers still fall short of national goals.
“We’re heartened by word that breast cancer screening rates have been relatively stable in the past decade, but more than concerned that we’re not meeting national targets for breast screenings across all population groups,” said Ambassador Nancy G. Brinker, Komen founder and CEO. “These figures underscore the need for more women to get educated and get screened if we are to make progress against breast cancer, which is still the number one cancer killer of women worldwide.”
Figures from the Centers for Disease Control and Prevention shows that overall, breast cancer screening rates in 2010 were 72.4 percent, well below the national target of 81 percent in CDC’s Healthy People 2020 goals.
Brinker said the positive news in the report is that screening rates for African American women – who are often diagnosed later or with more aggressive forms of breast cancer than Caucasians – is improving at 73.4 percent. Significant challenges remain to improve screening rates among Hispanic women (69.7 percent) and Asians (64.1 percent).
The most dismal numbers came for women without insurance (38.2 percent) or women without a usual source of health care (36.2 percent).
“This gap in care for uninsured and low-income women is particularly troubling and one we have been working very hard to fill at Susan G. Komen,” Brinker said. “It’s clear that we have far more work to do for women who have no resources, no insurance, and no steady source of healthcare. They need our help the most.”
Brinker said Komen for the Cure provided funds for more than 700,000 breast screenings for low-resource women in 2011, through programs with 2,000 community partners providing breast cancer education, health care, social support and financial aid. Since Komen’s founding in 1982, the organization has raised and funded more than $1.3 billion to community health programs across the U.S. through its network of 120-plus Affiliates.
Komen also provides special outreach to African American women through its Circle of Promise program, and to Hispanics through a new initiative, Lazos que Perduran, launched this year.
Komen’s Advocacy Alliance and Komen Affiliates have also been staunch advocates to continue or restore funding for low-income women through state programs and through the National Breast and Cervical Cancer Early Detection Program.
“We know that when women are reached early, educated about their risks and helped into screening, we can save a lot of lives,” Brinker said. “Death rates from breast cancer have dropped 31 percent in 20 years – largely the result of early detection coupled with better treatments. Five-year survival rates are now 99 percent from early stage breast cancers. We can save many, many women if we can get them educated, screened, and helped through treatment.”
More than 230,000 women will be diagnosed with breast cancer in the United States this year, with almost 40,000 deaths expected. Worldwide, breast cancer is the leading cause of cancer death in women, with almost half a million women expected to die of the disease this year.
Femara Tops Tamoxifen for Early Stage Breast Cancer
According to a recent article in The Lancet Oncology and Breast Cancer Org–Many postmenopausal women take hormonal therapy medicine — either an aromatase inhibitor or tamoxifen — after breast cancer surgery and other treatments for hormone-receptor-positive, early-stage breast cancer. Hormonal therapy medicine can reduce the risk of the cancer coming back (recurrence). Treatments given after surgery are called “adjuvant” — in this case adjuvant hormonal therapy.
The latest results from the BIG 1-98 trial found that the aromatase inhibitor Femara (chemical name: letrozole) was better at reducing the risk of recurrence and improving survival compared to tamoxifen when taken for 5 years as the first hormonal therapy after surgery.
The results were published early online on Oct. 21, 2011 in The Lancet Oncology.
In the BIG 1-98 trial, more than 8,000 postmenopausal women diagnosed with early-stage, hormone-receptor-positive breast cancer were randomly assigned one of four treatments after surgery:
- 5 years of Femara
- 5 years of tamoxifen
- 2 years of tamoxifen then 3 years of Femara (sequential therapy)
- 2 years of Femara then 3 years of tamoxifen (sequential therapy)
Half the women were followed for more than 8 years; the others for shorter times. The researchers then compared the outcomes of the different treatments.
Using two types of statistical analysis, the researchers found that women who got 5 years of Femara had:
- better disease-free survival (living without the cancer coming back)
- better overall survival (living whether or not the cancer came back)
compared to women who got 5 years of tamoxifen.
Women who got either of the sequential therapies (Femara for 2 years, then tamoxifen for 3, or tamoxifen for 2 years, then Femara for 3) had about the same recurrence risk, and the same overall survival, as women who got only Femara for 5 years.
Research continues to show that an aromatase inhibitor is the best hormonal therapy medicine after breast cancer surgery for postmenopausal women diagnosed with early-stage, hormone-receptor-positive breast cancer. Still, tamoxifen can be a good choice depending on a woman’s unique situation. Side effects and cost may make tamoxifen a better choice for some women. Sequential therapy also may allow some women to get the benefits of Femara without taking it for all 5 years.
When you’re deciding on a treatment plan after breast cancer surgery, keep two things in mind:
- Every woman responds differently to treatment. What works for you may not work for someone else.
- Your treatment plan isn’t written in stone. You can always switch medicines if another treatment has greater benefits and fewer side effects.
If you’re a postmenopausal woman being treated for hormone-receptor-positive, early-stage breast cancer, ask your doctor about the differences in benefits and side effects of aromatase inhibitors and tamoxifen. If you’re currently taking tamoxifen, discuss whether switching to an aromatase inhibitor makes sense for you. Together, you can decide on a treatment plan that is best for YOU.
Stress and the Immune System
Why do many people feel so much more stress at this time of year? We tend to blame worsening traffic, crowded malls, and incessant commercials pushing holiday consumption, but a key culprit is our own memories, according to Ronald Nathan, PhD, clinical professor at Albany Medical College in New York. “When we think about the holidays, we dwell on the past and what went wrong, or we romanticize it and make it impossible to re-create,” he says.
He counsels people to carefully examine their thoughts and expectations, and not drive themselves crazy finding “the perfect gift” or planning “the perfect party.” “Instead,” he says, “lower your expectations, and overestimate — rather than underestimate — your time.”
Easing up on yourself over the holidays is important because the connection between stress and illness is real, says Simon A. Rego, PsyD, an assistant professor of psychiatry and behavioral sciences at Albert Einstein College of Medicine and associate director of psychology training at Montefiore Medical Center in Bronx, N.Y.
“The controversy that stress causes disease is pretty much over. We’re now teasing out how stress does it,” he says. In fact, a new study explains how stress may weaken the immune system. Each cell contains a tiny “clock” called a telomere, which shortens each time the cell divides. To counter this effect, the body also produces an enzyme, telomerase, which protects the cell and prevents further shortening by adding more DNA to the end of the telomere.
So far, so good — but under stress, the body pumps out cortisol, a hormone that suppresses this protective enzyme. The study found that people under chronic stress have shorter telomeres, which, researchers say, means they are more vulnerable to a host of ailments.
Health effects of stress
How to reduce the wear, tear, and misery that holiday stress can inflict? When your holiday to-do list stretches longer than Santa Claus’s beard, eliminate whatever is unnecessary. Doing so may reduce your risk of:
-Heart disease, including heart attacks
-Skin conditions, including psoriasis and shingles
-Digestive disorder flare-ups, such as symptoms of irritable bowel syndrome, ulcerative colitis, and Crohn’s disease
-Immune disorders, including flare-ups of multiple sclerosis and lupus
-Anxiety, depression, and insomnia
-Worsening pain, if you already have a pain disorder such as arthritis, back pain, and muscle spasms”
Make sure to read our article on Massage Therapy for Stress Relief!
By: Charlotte Libov
Don’t Let “Stressmas” Ruin The Beauty of Your Holiday Season!
Keep Holiday Stress to a Minimum: Learn to Say No
For many of us, the holidays were magical in childhood, carefree times to be savored. But then we grew into hordes of harried adults, falling victim to the season’s high expectations. Holiday stress has become as much a tradition as the Christmas ham.
“People are overcommitted,” says Marc D. Skelton, PhD, PsyD, a psychologist in Laguna Niguel, Calif. “Christmas and other holidays around this time are always supposed to be fun, and you’re supposed to do a good job in terms of entertaining friends and family.”
In an attempt to live up to the season’s tall orders, “people will just run from pillar to post,” he says. It’s not even “Christmas” anymore, some of his clients lament. It’s “Stressmas.”
We also overload ourselves with inherited traditions, even when they no longer fit into our busy lives, says Elaine Rodino, PhD, a psychologist in Santa Monica, Calif. If one’s mother “baked a thousand cookies and gave them to everyone she knew,” Rodino says, “people feel obligated to follow the same kinds of things.”
But there is a secret to cutting holiday stress: Just say no.
You don’t have to bake all those cookies, Rodino says. “You can start your own traditions.”
And you can learn to say no to lots of other demands, too, including party invitations that don’t entice or a whopping gift list that could clean out a mall.
Holiday Stress-Reduction Tip: Decide What Matters Most
“The spirit of the holidays is gratitude and giving,” says Patti Breitman, co-author of the book How to Say No Without Feeling Guilty.
Only a Scrooge would dispute that generosity is admirable. “It’s very satisfying to offer support to the people we love, help out a neighbor, or do something positive for the community,” Breitman writes. But “the conflict arises when we continually agree to things that please everyone but ourselves or when we commit to tasks for which we have no time or desire.”
By saying “yes” to every holiday invitation and demand that comes your way, you could wind up exhausted and possibly broke. Instead, reflect on what you cherish most about the holidays, experts say, whether it’s sending greeting cards to maintain relationships, tree trimming, baking, religious observances, seeing family and friends, supporting a charitable cause, or just relaxing.
When you know your priorities, you can turn down the less important things, Breitman says. “It’s easier to say ‘no’ if you know what you’re saying ‘yes’ to.”
How to Say No to Holiday Stress
1. Say No to Parties That You Don’t Want to Attend
First, “Lavishly thank the person for inviting you,” Breitman says.
Then apply the “less is more” rule, she says. Skip the long-winded explanation in favor of something short, sweet, and general: “I’m sorry, but I already have plans for that day.”
1. Say No to Parties That You Don’t Want to Attend continued…
“Your plan may be to take a bubble bath because you’re stressed out. Or you’re renting a movie and having hot cocoa with your family,” Breitman says. “No one has to know what your commitment is.”
If the other person insists on knowing why you can’t come, the burden of prying will be on him, Breitman writes in her book. Don’t fall into the trap of coming up with new and creative excuses, she says. Instead, paraphrase yourself: “I won’t be able to come” or “I already have something on my calendar.”
If you receive an invitation from someone you genuinely want to see — just not during the hectic holiday season — suggest an alternative, Breitman says. For example, you can say, “I can’t make it to your party, but let’s have lunch after the holidays.”
2. Say No to Out-of-Control Gift-Giving
“Nothing saps the holiday spirit like having to run around and buy gifts you don’t have time to shop for, can’t afford, and that nobody really needs anyway,” Breitman says.
If you’re fed up, you can opt out of family gift-giving traditions “if you don’t mind looking like ‘the Grinch who said no to Christmas,’” she says.
Or you take a more tactful approach. Consider drawing names for a gift exchange or buying one gift for a household instead of individual presents. Or experiment with novel alternatives:
- Pool your money and invest in a professionally done family portrait, with prints for everyone.
- Replace material things with a memorable holiday experience. Rent a house in a vacation spot or national park, or gather everyone to attend a special holiday play or performance.
Gift cards to family and friends can be a godsend. But Breitman offers another twist — especially for those on your list who don’t need another cheese gift basket or motorized tie rack.
Tell them, “I’m starting a new tradition. Instead of giving gifts, I’m going to make a contribution to an organization in your honor.”
3. Say No to Unwanted Houseguests
Your cousin — the one who recalls at every family gathering how you got stuck in the dog door trying to sneak out of the house in high school — wants to move his brood into your home for a week, but you know that you’ll end up getting on each other’s nerves.
“Keeping houseguests away is a lot easier than getting rid of them,” Breitman warns. “Once they’re under your roof, it’s almost impossible to evict someone in a graceful, guilt-free manner.”
Some preventive tactics:
- “You’re coming to town? Fantastic! A great new hotel just opened — you’ll love it!”
- “Sorry, the house is in no condition for guests right now.”
- “I can’t wait to see you. Do you need recommendations on a good place to stay?”
4. Say No to Taking On the Work for a Big Holiday Celebration
Are you the family’s Martha Stewart? The one who knocks herself out every Christmas to prepare an elaborate feast for the extended clan?
If festive entertaining leaves you frazzled, Breitman suggests a change of scenery. For example, say, “Everyone has been coming here for Christmas for years, but I need a break. Either someone else can do it or we’ll all go out to a restaurant.”
If you still plan to host, but don’t want to shoulder the entire burden, the word “tradition” carries extra clout during the holidays, Breitman says. Use it to your advantage. Tell your guests, “I’m starting a new tradition. This year, everyone will bring one dish for the meal.”
Because others are busy, too, “Make sure that they understand that no one has to make it from scratch,” Breitman says.
It’s fine if Grandma’s soup came from the deli or your nephew shows up with store-bought dinner rolls. As Martha likes to say, it’s a good thing.
Leading Breast Cancer Organization Comments on Long Term Mammography for Breast Cancer Survivors
BREASTCANCER.ORG SAYS:
Women who’ve been diagnosed with breast cancer are at risk for the cancer coming back (recurrence) and also have a higher-than-average risk of being diagnosed with a new, second breast cancer. So regular breast cancer screening is very important for survivors.
To find out if doctors were recommending breast cancer screening to survivors, researchers surveyed British physicians who care for women diagnosed with breast cancer. The researchers also reviewed the results of eight studies on the benefits of ongoing breast cancer screening for survivors.
The results:
- Doctors didn’t consistently recommend ongoing, long-term breast cancer screening for survivors.
- Ongoing, long-term screening for survivors is lifesaving: women who were screened consistently for 10 years or more were 72% less likely to die from recurrent or new breast cancer compared to women who didn’t get consistent, long-term screening.
- The risk of a recurrence or a new, second breast cancer was about the same during each of the 10 years after diagnosis. Most people think that if breast cancer is going to come back or a new cancer to develop, it will be in the first 2 or 3 years after diagnosis — this study found that isn’t the case.
The results were published in the September 2011 issue of Health Technology Assessment.
These results underscore the importance of long-term, regular screening mammograms for survivors. Still, other research has shown that mammograms alone can be less effective at detecting breast cancer in women with a personal history of breast cancer. Survivors may benefit from other screening tests — such as breast MRI or breast ultrasound — in addition to screening mammograms. Some experts think that screening with 3-D mammograms also may be especially useful for survivors. The FDA has approved a 3-D mammogram system, but the technology may not be widely available.
If you’ve been diagnosed with breast cancer, you and your doctor should develop a screening plan tailored to your unique situation. If the plan includes only regular mammograms, you may want to ask your doctor if breast MRI or ultrasound along with mammograms might make sense for you. No matter what your screening plan includes, be sure to stick with it over the long term, not just in the first few years after you’ve finished treatment.
Long Term Mammography Needed for Breast Cancer Survivors
(MedPage Today) –Regular surveillance mammography after breast cancer boosts survival and should be continued for at least a decade, a systematic review suggested.
Second cancers in the same or opposite breast occurred at a fairly constant rate over the first 10 years instead of being largely in the first two or three years as often thought, Clare Robertson, MSc, of the University of Aberdeen, Scotland, and colleagues found.
Mammographic follow-up to detect these tumors was associated with reduced all-cause mortality and breast cancer-specific mortality in the studies reviewed.
Because the analysis also presented favorable data regarding cost-effectiveness, the group argued online in Health Technology Assessment for routine surveillance mammography out to at least 10 years.
- Yearly surveillance mammography after breast cancer boosts survival and should be continued for at least a decade.
- Note that surveillance mammography for breast cancer survivors appeared to be cost-effective.
Annual surveillance after breast cancer surgery is recommended in guidelines from the American Society of Clinical Oncology, and is common practice in both Britain and the United States.
The researchers surveyed 183 surgeons and radiologists at 105 British centers and found that most stopped following women with surveillance mammography (74%). Slightly over half said they stop at 10 years, though discontinuation at five years was also common at 35%.
Though surveillance schedules varied widely, follow-up mammography usually started at 12 months (87%), repeated annually (72%), and was coordinated using a symptomatic breast service (96%).
Most clinicians surveyed also reported discharging women from clinical follow-up (82%), typically at five years after breast cancer surgery (65%).
The researchers cautioned that their response rate was low (17% of 1,048 surveys sent out) but noted that the responses correlated fairly well with prior surveys on the topic and were likely representative.
The review also looked at the eight cohort studies that have reported on the mortality impact of surveillance mammography among breast cancer survivors.
All suggested a benefit of routine follow-up, though methods differed sufficiently to preclude pooled analysis.
All-cause mortality was 34% lower with yearly surveillance mammography than without it (age-adjusted odds ratio 0.66, 95% confidence interval 0.51 to 0.86) in one study.
Breast cancer-specific mortality was 72% lower with surveillance mammography (multivariate adjusted hazard ratio 0.28, 95% CI 0.22 to 0.37) in another study.
The smaller tumors that could only be found with imaging were associated with better survival odds than larger tumors among these women as well, the group reported.
Tumors larger than 20 mm in diameter — which represent about 80% of those detected with mammography done every three years — independently raised the relative risk of death 2.26-fold compared to those under 10 mm in diameter (95% CI 1.58 to 3.24).
Tumors with missing size data, which likely were those of women who did not have surgery, were associated with 3.19-fold higher risk of death (95% CI 2.24 to 4.53).
“While we have no information as to how these events were detected in clinical practice, the implication is that surveillance mammography may be of value,” Robertson’s group wrote, since it suggests, “that surveillance mammography could be used to reduce the size at which ipsilateral breast tumor recurrence or [second contralateral] cancers are detected.”
Yearly mammography alone, without additional clinical examination, appeared to be the regimen with the biggest net benefit and most likely to be considered cost-effective in the group’s economic analysis.
The incremental cost of yearly surveillance mammography was $7,364 (£4,727) per quality-adjusted life-year compared with no surveillance, falling well below the traditional British regulatory threshold of £30,000 for cost-effectiveness.
But for lower risk women, such as the 70-year-old in the scenario modelled, “it may be more cost-effective for surveillance to be performed less often (every two or three years) with mammography alone or another similarly less intensive and less costly test or combination of tests,” the group wrote.
They acknowledged the paucity of data available to go into the economic models, making it an exploratory analysis that should be interpreted cautiously.
By Crystal Phend, Senior Staff Writer, MedPage Today
Published: October 02, 2011
Reviewed by Robert Jasmer, MD; Associate Clinical Professor of Medicine, University of California, San Francisco and
Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner
National Women’s Health Week May 8-14, 2011
The 9th annual National Women’s Checkup Day will be held on Monday, May 9, 2011, during National Women’s Health Week. The day is dedicated to encouraging women to visit health care professionals to receive or schedule a checkup and promoting regular checkups as vital to the early detection of breast cancer, heart disease, diabetes, other types of cancer, and many other conditions.
National Women’s Checkup Day is a nation wide effort coordinated by the Department of Health and Human Services Office on Women’s Health to:
- Encourage women to visit their health care providers to receive or schedule a checkup.
- Promotion of regular checkups as vital to the early detection of illnesses and other conditions.
It is important for women to get regular checkups because:
- Screenings tests such as mammograms can find and detect breast cancer early, when it is easier to treat. Some women may need certain tests earlier or more often than others.
- Screenings and routine care can help women lower their risks of many health conditions early including breast cancer and heart disease.
How can you participate in this important event?
- Contact your physician or local health clinic to schedule screenings or checkups on Nationl WOmen’s Checkup Day.
- During your checkup discuss what screenings and tests are right for you, when you should have them and how often.
- Take the CheckUp Day Pledge and Pledge to schedule at least one preventive health screenings during the month of May.
- Click here for the Interactive Screening Chart and Immunization Tool to determine what screenings and immunizations you need and at what age.
- Take the Pledge:
As a participant in National Women’s Checkup Day, I will:
- Contact my current doctor or nurse to schedule checkups and screening services;
- Use the interactive screening chart and immunization tool to learn what screenings and immunizations I need and at what age;
- Discuss with my health care professional during my checkup which of the tests are right for me, when I should have them, and how often;
- Schedule an appointment for at least one of the preventive health screenings during May 2011
Click here I’m ready to take the pledge! to select your state and then click Submit My Pledge to commit to a Healthier You! Print out your Certificate like the one below!
Obesity Boosts Risk for Aggressive Breast Cancer
March 1, 2011 — Obesity and a sedentary lifestyle appear to increase the risk for an uncommon but aggressive breast cancer that is not fueled by the hormone estrogen, a surprising new study shows.
The analysis of data from a health study involving postmenopausal women revealed that the heaviest women were 35% more likely to develop so-called triple-negative breast cancers than the thinnest women.
Triple-negative breast cancers make up 10% to 20% of all cancers of the breast. They have a poorer prognosis than other tumors, in part because there are no targeted hormonal therapies to treat them.
They are referred to as triple-negative tumors because they do not express the hormones estrogen and progesterone or HER2 protein.
Fat tissue is a significant source of estrogen production in women and obesity is a known risk factor for estrogen-sensitive tumors.
The finding that obesity also appears to raise the risk for triple-negative tumors, which are not fueled by estrogen, was unexpected, study researcher Amanda I. Phipps, PhD, tells WebMD.
Phipps is a postdoctoral fellow at Seattle’s Fred Hutchinson Cancer Research Center.
“Hormones are one pathway by which obesity can impact cancer growth, but there are others,” Phipps says. “The fact that we see this association with triple-negative tumors suggests that these other pathways are important.”
Exercise, Body Mass Index, and Cancer Risk
The analysis included 155,723 participants enrolled in the Women’s Health Initiative (WHI), which followed postmenopausal women for 15 years starting in the early 1990s to assess their risk for cancer, heart disease, and osteoporosis.
During about eight years of follow-up, 307 of the study participants were diagnosed with triple-negative breast cancers and 2,610 were found to have estrogen-sensitive breast cancers.
The women in the study were divided into four groups according to body mass index (BMI).
Compared to women with the lowest BMIs, those with the highest were 39% more likely to be diagnosed with estrogen-sensitive tumors and 35% more likely to have triple-negative tumors.
Compared to women who exercised the least, those who exercised the most were 15% less likely to develop estrogen-sensitive tumors.
The study appears in the March 1 issue of Cancer Epidemiology, Biomarkers & Prevention.
African-Americans, Younger Women Have Higher Risk
Triple-negative breast cancers are common among women who have a genetic predisposition known as BRCA1, and they also occur more often in African-American women and tend to occur in younger women.
While none of these risk factors is modifiable, Phipps says the new study suggests two potential interventions that may lower a woman’s risk for developing the disease.
“There are already hundreds of reasons for women to maintain a healthy weight and remain physically active,” she says. “This may be one more.”
University of Wisconsin associate professor Amy Trentham-Dietz, PhD, agrees.
“These findings suggest that avoiding obesity and staying active could lower a woman’s risk for all types of breast cancer, not just those that are estrogen-receptor positive,” she tells WebMD. “That is a very positive message.”
Number of Childbirths and Cancer Risk
Triple-negative breast cancers were first identified less than a decade ago, and Phipps says they are still something of a mystery to researchers and doctors.
Findings from a separate analysis of the WHI data, reported last week by Phipps and colleagues, also surprised the researchers. That study was published Feb. 24 online in the Journal of the National Cancer Institute.
The analysis suggested that the more children a woman has delivered, the higher her risk for the cancer. Women in the study who had never given birth had a 40% lower risk for triple-negative cancers than women who had.
Childbirth is known to be protective against estrogen-receptor positive breast cancers.







